OG LA Grapefruit is a longtime marijuana classic, a heady blend of the hybrid Cinderella 99 and a sativa bred specifically for its grapefruit flavor. With a sativa/indica ratio of 70:30, this strain packs a decidedly cerebral punch, with a major mood boost and intense euphoria. High THC levels have been charted so this is a pretty powerful strain. CBD levels, meanwhile, are very low, ruling this out as an effective treatment for epilepsy. But it’s highly effective at relieving anxiety and depression, as well as pain, GI distress, and PMS. This strain is highly appealing to smokers looking for a strong head high.